Kalpana Ghoshal

Associate Professor, Dept. of Pathology
Mentor Faculty

 

Research Description:

My lab focuses on elucidating the functions of microRNAs and the factors involved in DNA methylation/hydroxymethylation in liver biology and the consequence of their deregulation in liver disease such as alcoholic and nonalcoholic fatty liver disease, drug-induced liver toxicity and liver cancer.  We utilize primary hepatocytes, cells culture and mouse models as well as diseased liver tissues from patients to better understand the role of these factors in liver biology and disease processes.  The goal of the lab is to understand the role of microRNAs in modulating metabolism in the liver and hepatocellular cancer, and to develop novel therapies for various liver diseases including hepatocellular cancer (HCC).

Areas of Expertise
  • Cancer
  • Molecular Basis of Disease
  • MicroRNA
  • Metabolism
Education
  • BS, Calcutta, 1978
  • PhD, Calcutta, 1988
  • Postdoctoral, Chicago Medical School, 1988-1992

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Phone:
614-292-8865
Fax:
614-292-4118
646C Tzagournis Med Res Fac
420 West 12th Avenue
Columbus OH 43210