Zebrafish have the profound ability to regenerate damaged heart muscle. My research is focused on how this capacity to regenerate is controlled at the level of gene expression. Using transgenic and mutant fish models, I am dissecting the specific molecules that regulate transcription and chromatin dynamics in the zebrafish heart. The goal is to uncover new pathways and paradigms in what distinguishes heart regeneration in the zebrafish versus scarring and myopathy in humans.