Research Description:

Our laboratory studies several different aspects of skeletal muscle and cardiovascular physiology, principally focusing on changes in plasma membrane repair, cellular metabolism and calcium homeostasis in normal physiology and disease states. While relevant in normal physiology, disruption of these processes contributes to a number of diseases, including muscular dystrophy, ischemic damage to the heart and neurodegeneration. We use biochemical, cell based assays and animal model to study these processes with a particular emphasis on confocal microscopy and muscle physiology approaches. Our current funding comes from the NIH, American Heart Foundation and the Jain Foundation.