Publications

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Title Investigators Year
Acetylation of histone H3 at the nucleosome dyad alters DNA-histone binding Justin North, Michael Poirier, Jonathan W Picking (OSBP alumni), Mridula Manohar, Alex M Mooney, Robin J Nakkula, Annick Edon, Richard Fishel, Jennifer J Ottesen 2009
Phosphorylation of histone H3(T118) alters nucleosome dynamics and remodeling Justin North, Michael Poirier, Jonathan W Picking (OSBP alumni), Sarah Javaid, Michelle B Ferdinand, Nilanjana Chatterjee, Matthew Shoffner, Robin J Nakkula, Blaine Bartholomew, Jennifer J Ottesen, Richard Fishel 2011
Preparation of fully synthetic histone H3 reveals that acetyl-lysine 56 facilitates protein binding within nucleosomes Justin North, Michael Poirier, John C Shimko (OSBP alumni), Aaron N Bruns (OSBP alumni), Jennifer J Ottesen 2011
ATP-dependent nucleosome unwrapping catalyzed by human RAD51 Justin North, Michael Poirier, Aarons N Burns (OSBP alumni), Ravindra Amunugama, Marcelina Klajner, Richard Fishel 2013
Histone H3 phosphorylation near the nucleosome dyad alters chromatin structure Justin North, Michael Poirier, Jonathan W Picking (OSBP alumni), Cecil J Howard (OSBP alumni), Marek Simon, Michelle B Ferdinand, Matthew A Shoffner, Alex M Mooney, John van Noort, Jennifer J Ottesen 2014
Chemical and biological tools for the preparation of modified histone proteins Miranda Gardner, Cecil J Howard (OSBP alumni), Ruixuan R Yu (OSBP alumni), John Shimko (OSBP alumni), Jennifer J Ottesen 2015
Conferring resistance to geminiviruses with the CRISPR-Cas prokaryotic immune system David Bisaro, Aaron N Burns (OSBP alumni), Nicholas J Baltes, Aaron W Hummel, Eva Konecna, Radim Cegan, Daniel F Voytas 2015
Determination of Protein Surface Hydration by Systematic Charge Mutations Dongping Zhong, Dihao Wang (OSBP alumni), Menghui Jia, Jin Yang, Yangzhong Qin, Haifeng Pan, Lijuan Wang, Jianhua Xu 2015
Kinesin's front head is gated by the backward orientation of its neck linker Vedud Purde (OSBP alumni), Merve Yusra Dogan, Sinan Can, Frank B Cleary, Ahmet Yildiz 2015
SMN expression is required in motor neurons to rescue electrophysiological deficits in the SMNΔ7 mouse model of SMA Anton Blatnik, Arthur Burghes, Vicki McGovern, Chitra C Iyer, W David Arnold, Sara E Gombash, Phillip G Zaworski, Kevin D Foust 2015
A mutation in the THG1L gene in a family with cerebellar ataxia and developmental delay Jane Jackman, Ashanti Matlock (OSBP alumni), Simon Edvardson, Yael Elbaz-Alon, Chaim Jalas, Krishna Patel, Katherine Labbe, Avraham Shaag, Orly Elpeleg 2016
An elastic element in the protocadherin-15 tip link of the inner ear Brandon Neel, Marcos Sotomayor, Raul Araya-Secchi 2016
An internal electron reservoir enhances catalytic CO2 reduction by a semisynthetic enzyme Camille R Schneider (OSBP alumni), Hannah S Shafaat 2016
Molecular Origin of Ultrafast Water-Protein Coupled Interactions Dongping Zhong, Dihao Wang (OSBP alumni), Yangzhong Qin, Menghui Jia, Jin Yang, Lijuan Wang, Jianhua Xu 2016
Real-Time Visualization and Quantification of Contractile Ring Proteins in Single Living Cells Jian-Qiu Wu, Kenneth S Gerien (OSBP alumni), Reshma Davidson, Yajun Liu 2016
Accessibility of the histone H3 tail in the nucleosome for binding of paired readers Nathaniel Burge, Michael Poirier, Jovylyn Gatchalian, Xiaodong Wang, Jinzen Ikebe, Khan L Cox, Adam H Tencer, Yi Zhang, Luo Di, Matthew D Gibson, Catherine A Musselman, Hidetoshi Kono, Jeffrey J Hayes, Tatiana G Kutateladze 2017
Conformational and chemical selection by a trans-acting editing domain Kotaro Nakanishi, Mark Foster, Karin Musier-Forsyth, Eric M Danhart (OSBP alumni), Alexandra B Kuzmishin (OSBP alumni), Marina Bakhtina, William A Cantara, Xiao Ma, Brianne L Sanford, Oscar Vargas-Rodriguez, Marija Kosutic, Yuki Goto, Hiroaki Suga, Ronald Micura 2017
Conserved GTPase LepA (Elongation Factor 4) functions in biogenesis of the 30S subunit of the 70S ribosome Kurt Fredrick, Menglin Chen (OSBP alumni), Rohan Balakrishnan (OSBP alumni), Michelle R Gibbs, Kyung-Mee Moon, Leonard J Foster 2017
Human Argonaute3 has slicer activity Hong Duc Chau Phan, Vicki Wysocki, Kotaro Nakanishi, Samantha H Hinckley (OSBP alumni), Mi Seul Park, Florian Busch, James A Brackbill 2017
Light-Driven Hydrogen Evolution by Nickel-Substituted Rubredoxin Camille R Schneider (OSBP alumni), Michael J Stevenson, Sean C Marguet, Hannah S Shafaat 2017
Multielectron Chemistry within a Model Nickel Metalloprotein: Mechanistic Implications for Acetyl-CoA Synthase Anastasia C Manesis (OSBP alumni), Camille R Schneider (OSBP alumni), Matthew J O'Connor, Hannah S Shafaat 2017
Variable phenotypic expression and onset in MYH14 distal hereditary motor neuropathy phenotype in a large, multigenerational North American family Arthur Burghes, Stephen Kolb, Corey Ruhno (OSBP alumni), Stanley Iyadurai, W David Arnold, John T Kissel, Vicki L McGovern, Pamela J Snyder, Thomas W Prior, Jennifer Roggenbuck 2017
A photoactive semisynthetic metalloenzyme exhibits complete selectivity for CO2 reduction in water Camille R Schneider (OSBP Alumni), Anastasia C Manesis (OSBP alumni), Michael J Stevenson, Hannah S Shafaat 2018
Conserved structural and functional aspects of the tripartite motif gene family point towards therapeutic applications in multiple diseases Noah Weisleder, Thomas A Kwiatkowski (OSBP alumni), Liubov V Gushchina, Sayak Bhattacharya 2018
Identification of Unknown Metabolomics Mixture Compounds by Combining NMR, MS, and Cheminformatics Abigail Leggett, Rafael Brüschweiler, Cheng Wang, Da-Wei Li, Arpad Somogyi, Lei Bruschweiler-Li 2018