Publications

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Title Investigators Year
Photorhabdus luminescens TccC3 Toxin Targets the Dynamic Population of F-Actin and Impairs Cell Cortex Integrity. Songyu Dong, Sarah Heissler, Dmitri Kudryashov, Zheng W, Pinkerton N, Hansen J, Tikunova SB, Davis JP, Kudryashova E, Egelman EH 2022
Plant-exclusive domain of trans-editing enzyme ProXp-ala confers dimerization and enhanced tRNA binding Jun-Kyu Byun, Karin Musier-Forsyth, John A Vu, Siou-Luan He, Jyan-Chyun Jang 2022
Protein Structure Prediction with Mass Spectrometry Data. Sarah Biehn, Steffen Lindert 2022
Proteomic analysis of the umbilical cord in fetal growth restriction and preeclampsia. Miranda Gardner, Michael Freitas, Matthew S Conrad, Christine Miguel, Kara M Rood, Marwan Ma'ayeh 2022
Pulsed Multifrequency Electron Paramagnetic Resonance Spectroscopy Reveals Key Branch Points for One- vs Two-Electron Reactivity in Mn/Fe Proteins Hannah Shafaat, Effie Kisgeropoulos (OSBP alumni), Yunqiao J Gan, Samuel M Greer, Joseph M Hazel 2022
Structural basis for sequence-independent substrate selection by eukaryotic wobble base tRNA deaminase ADAT2/3. Aubree Zimmer, Juan Alfonzo, Dolce LG, Tengo L, Weis F, Rubio MAT, Kowalinski E 2022
Structure of a RecT/Redβ family recombinase in complex with a duplex intermediate of DNA annealing Brian Caldwell, Vicki Wysocki, Charles Bell, Andrew S Norris, Caroline F Karbowski, Alyssa M Wiegand 2022
Tackling antimicrobial stewardship through synergy and antimicrobial peptides. Jenna Greve, James Cowan 2022
The Mechanical Microenvironment Regulates Axon Diameters Visualized by Cryo-Electron Tomography Di Ma, Chen Gu, Binbin Deng, Chao Sun, David W McComb 2022
Thioester synthesis by a designed nickel enzyme models prebiotic energy conversion. Alina Yerbulekova, Hannah Shafaat, Manesis AC, Shearer J 2022
Tied up in knots: Untangling substrate recognition by the SPOUT methyltransferases Isobel Bowles, Jane Jackman, Sarah E Strassler , Debayan Dey, Graeme L Conn 2022
Validated determination of NRG1 Ig-like domain structure by mass spectrometry coupled with computational modeling. Sarah Biehn, Steffen Lindert, Khaje NA, Eletsky A, Mobley CK, Rogals MJ, Kim Y, Mishra SK, Doerksen RJ, Prestegard JH, Sharp JS 2022
A review on structural, non-structural, and accessory proteins of SARS-CoV-2: Highlighting drug target sites. Md Siddik Alom, Jahirul Islam M, Nawal Islam N, Kabir M, Halim MA 2023
An Hspa8 variant is a shocking modifier of spinal muscular atrophy in mice. Anton Blatnik, Arthur Burghes 2023
Analyzing protein posttranslational modifications using enzyme-catalyzed expressed protein ligation. Niyi Adelakun, Nam Chu, Jordan Parrish 2023
Base editing rescue of spinal muscular atrophy in cells and in mice Kaitlyn Kray, Anton Blatnik, Arthur Burghes, Mandana Arbab, Zaneta Matuszek, Ailing Du, Gregory A Newby, Aditya Raguram, Michelle F Richter, Kevin T Zhao, Jonathan M Levy, Max W Shen, W David Arnold, Dan Wang, Jun Xie, Guangping Gao, Daivd R Liu 2023
CRISPR-Cas has a new juggling act: interplay between nuclease and protease. Anthony Rish, Tianmin Fu 2023
Diversity in Biological Function and Mechanism of the tRNA Methyltransferase Trm10 Isobel Bowles, Jane Jackman 2023
DJ-1 Molecular Chaperone Activity Depresses Tau Aggregation Propensity through Interaction with Monomers. Claire Hoffman, Vicki Wysocki, Jeff Kuret, Jimenez-Harrison D, Huseby CJ, Sher S, Snyder D, Seal B, Yuan C, Fu H, Giorgini F 2023
Engineered Extracellular Vesicles Derived from Dermal Fibroblasts Attenuate Inflammation in a Murine Model of Acute Lung Injury. Julian Aldana Aroca, Ana I Salazar-Puerta, Maria A Rincon-Benavides, Tatiana Z Cuellar-Gaviria, Gabriela Vasquez Martinez, Lilibeth Ortega-Pineda, Devleena Das, Daniel Dodd, Charles A Spencer, Binbin Deng, David W McComb, Joshua A Englert, Samir Ghadiali, Diana Zepeda-Orozco, Loren E Wold, Daniel Gallego-Perez, Natalia Higuita-Castro 2023
Enhancement of Lipid Signals in Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry with Ammonium Fluoride as a Matrix Additive Joseph Holbrook, Amanda Hummon, Emily R Sekera, Arbil Lopez, Brian D Fries, Fernando Tobias, Kubra Akkaya, Maria M Mihaylova 2023
How to Build a Metalloenzyme: Lessons from a Protein-Based Model of Acetyl Coenzyme A Synthase Hannah Shafaat, Alina Yerbulekova, Anastasia Manesis (OSBP alumni) 2023
Identification of Small-Molecule Inhibitors of the Salmonella FraB Deglycase Using a Live-Cell Assay. Jamison Law, Venkat Gopalan, Anice Sabag-Daigle, Erin F Boulanger, Pankajavalli Thirugnanasambantham, Alex J Bogard, Edward J Behrman, Brian M M Ahmer 2023
Increased levels of eIF2A inhibit translation by sequestering 40S ribosomal subunits Daisy Grove, Michael Kearse, Daniel J Levine 2023
Molecular mechanisms of Holliday junction branch migration catalyzed by an asymmetric RuvB hexamer Anthony Rish, Qingfei Zheng, Tianmin Fu, Zhangfei Shen, Zhenhang Chen, Nan Zhang 2023