Publications

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Title Investigators Year
Inhibition of HIV-1 Gag-membrane interactions by specific RNAs Gabrielle C Todd, Alice Duchon, Jingga Inlora, Erik D Olson, Karin Musier-Forsyth, Akira Ono 2017
Light-Driven Hydrogen Evolution by Nickel-Substituted Rubredoxin Camille R Schneider (OSBP alumni), Michael J Stevenson, Sean C Marguet, Hannah S Shafaat 2017
Microtubules are reversibly depolymerized in response to changing gaseous microenvironments within Aspergillus nidulans biofilms Nandini Shukla, Aysha H Osmani, Stephen A Osmani 2017
Multielectron Chemistry within a Model Nickel Metalloprotein: Mechanistic Implications for Acetyl-CoA Synthase Anastasia C Manesis (OSBP alumni), Camille R Schneider (OSBP alumni), Matthew J O'Connor, Hannah S Shafaat 2017
Pathogenic Mechanisms of Actin Cross-Linking Toxins: Peeling Away the Layers Elena Kudryashova, David B Heisler, Dmitri S Kudryashov 2017
RCAN1-4 is a thyroid cancer growth and metastasis suppressor Chaojie Wang, Motoyasu Saji, Steven E Justiniano, Adlina Mohd Yusof, Xiaoli Zhang, Lianbo Yu, Soledad Fernández, Paul Wakely Jr, Krista La Perle, Hiroshi Nakanishi, Neal Pohlman, Matthew D Ringel 2017
Renin-angiotensin-aldosterone system inhibitors improve membrane stability and change gene-expression profiles in dystrophic skeletal muscles Jessica A Chadwick, Sayak Bhattacharya, Jeovanna Lowe, Noah Weisleder, Jill A Rafael-Fortney 2017
RNA guanine-7 methyltransferase catalyzes the methylation of cytoplasmically recapped RNAs Jackson B Trotman, Andrew J Giltmier, Chandrama Mukherjee, Daniel R Schoenberg 2017
Stromal PDGFR-α Activation Enhances Matrix Stiffness, Impedes Mammary Ductal Development, and Accelerates Tumor Growth Anisha M Hammer, Michael C Ostrowski 2017
The ETS family of oncogenic transcription factors in solid tumours Gina M Sizemore, Jason R Pitarresi, Subhasree Balakrishnan, Michael C Ostrowski 2017
The Evolution of Substrate Specificity by tRNA Modification Enzymes Katherine M McKenney, Mary Anne T Rubio, Juan D Alfonzo 2017
Variable phenotypic expression and onset in MYH14 distal hereditary motor neuropathy phenotype in a large, multigenerational North American family Arthur Burghes, Stephen Kolb, Corey Ruhno (OSBP alumni), Stanley Iyadurai, W David Arnold, John T Kissel, Vicki L McGovern, Pamela J Snyder, Thomas W Prior, Jennifer Roggenbuck 2017
A 3E8.scFv.Cys-IR800 Conjugate Targeting TAG-72 in an Orthotopic Colorectal Cancer Model Li Gong, Haiming Ding, Nicholas E Long, Brandon J Sullivan, Edward W Martin Jr, Thomas J Magliery, Michael F Tweedle 2018
A photoactive semisynthetic metalloenzyme exhibits complete selectivity for CO2 reduction in water Camille R Schneider (OSBP Alumni), Anastasia C Manesis (OSBP alumni), Michael J Stevenson, Hannah S Shafaat 2018
Actin Cross-Linking Toxin Is a Universal Inhibitor of Tandem-Organized and Oligomeric G-Actin Binding Proteins Elena Kudryashova, David B Heisler, Blake Williams, Alyssa J Harker, Kyle Shafer, Margot E Quinlan, David R Kovar, Dimitrios Vavylonis, Dmitri S Kudryashov 2018
Binding synergy as an essential step for tRNA editing and modification enzyme codependence in Trypanosoma brucei Katherine M McKenney, Mary Anne T Rubio, Juan D Alfonzo 2018
Conserved structural and functional aspects of the tripartite motif gene family point towards therapeutic applications in multiple diseases Noah Weisleder, Thomas A Kwiatkowski (OSBP alumni), Liubov V Gushchina, Sayak Bhattacharya 2018
Disruption of stromal hedgehog signaling initiates RNF5-mediated proteasomal degradation of PTEN and accelerates pancreatic tumor growth Jason R Pitarresi, Anisha M Hammer, Michael C Ostrowski 2018
Five Residues in the Apical Loop of the Respiratory Syncytial Virus Fusion Protein F2 Subunit Are Critical for Its Fusion Activity Stephanie N Hicks, Supranee Chaiwatpongsakorn, Heather M Costello, Jason S McLellan, William Ray, Mark E Peeples 2018
Identification of Unknown Metabolomics Mixture Compounds by Combining NMR, MS, and Cheminformatics Abigail Leggett, Rafael Brüschweiler, Cheng Wang, Da-Wei Li, Arpad Somogyi, Lei Bruschweiler-Li 2018
IL-6 and PD-L1 antibody blockade combination therapy reduces tumour progression in murine models of pancreatic cancer Thomas A Mace, Reena Shakya, Jason R Pitarresi, Benjamin Swanson, Christopher W McQuinn, Shannon Loftus, Emily Nordquist, Zobeida Cruz-Monserrate, Lianbo Yu, Gregory Young, Xiaoling Zhong, Teresa A Zimmers, Michael C Ostrowski, Thomas Ludwig, Mark Bloomston, Tanios Bekaii-Saab, Gregory B Lesinski 2018
Linker engineering in anti-TAG-72 antibody fragments optimizes biophysical properties, serum half-life, and high-specificity tumor imaging Nicholas E Long, Brandon J Sullivan, Haiming Ding, Stephanie Doll, Michael A Ryan, Charles L Hitchcock, Edward W Martin Jr, Krishan Kumar, Michael F Tweedle, Thomas J Magliery 2018
Measures of single- versus multiple-round translation argue against a mechanism to ensure coupling of transcription and translation Kurt Fredrick, Menglin Chen (OSBP alumni) 2018
Molecular Dynamics and Umbrella Sampling Simulations Elucidate Differences in Troponin C Isoform and Mutant Hydrophobic Patch Exposure Steffen Lindert, Jacob D Bowman (OSBP alumni) 2018
Molecular mechanisms of contractile-ring constriction and membrane trafficking in cytokinesis Jian-Qiu Wu, Kenneth S Gerien (OSBP alumni) 2018