Publications

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Title Investigators Year
5'-End sequencing in Saccharomyces cerevisiae offers new insights into 5'-ends of tRNAHis and snoRNAs Jane Jackman, Samantha Dodbele (OSBP alumni), Blythe Moreland, Spencer M Gardner, Ralf Bundschuh 2019
A Microfluidic Chip Enables Isolation of Exosomes and Establishment of Their Protein Profiles and Associated Signaling Pathways in Ovarian Cancer Miranda Gardner, Michael Freitas, Kalpana Deepa Priya Dorayappan, Colin L Hisey, Roman A Zingarelli, Brentley Q Smith, Michelle D S Lightfoot, Rajan Gogna, Meghan M Flannery, John Hays, Derek J Hansford, Lianbo Yu, David E Cohn, Karuppaiyah Selvendiran 2019
A Temporal Order in 5'- and 3'- Processing of Eukaryotic tRNAHis Jane Jackman, Tracy M Roach (OSBP alumni), Marie-Theres Pohler, Heike Betat, Mario Morl 2019
Chemical footprinting and kinetic assays reveal dual functions for highly conserved eukaryotic tRNAHis guanylyltransferase residues Jane Jackman, Ashanti O Matlock (OSBP alumni), Brian A Smith (OSBP alumni) 2019
Complete sequencing of the SMN2 gene in SMA patients detects SMN gene deletion junctions and variants in SMN2 that modify the SMA phenotype Arthur Burghes, Corey Ruhno (OSBP alumni), Vicki L McGovern, Matthew R Avenarius, Pamela J Snyder, Thomas W Prior, Flavia C Nery, Abdurrahman Muhtaseb, Jennifer S Roggenbuck, John T Kissel, Valerie A Sansone, Jennifer J Siranosian, Alec J Johnstone, Pann H Nwe, Ren Z Zhang, Kathryn J Swoboda 2019
Computational Studies of Cardiac and Skeletal Troponin Steffen Lindert, Jacob D Bowman (OSBP alumni) 2019
Crystal structure of the Redβ C-terminal domain in complex with λ Exonuclease reveals an unexpected homology with λ Orf and an interaction with Escherichia coli single stranded DNA binding protein Brian Caldwell, Jordan Hempfling, Dehua Pei, Charles Bell, Ekaterina Zakharova, Gabriel T Filsinger, Timothy M Wannier, Lee Chun-Der, George M Church 2019
Determinants of target prioritization and regulatory hierarchy for the bacterial small RNA SgrS Tina Henkin, Jane K Frandsen (OSBP alumni), Maksym Bobrovskyy, Muhammad S Azam, Jichuan Zhang, Anustup Poddar, Xiangqian Ma, Taekjip Ha, Carin K Vanderpool 2019
Distinct substrate specificities of the human tRNA methyltransferases TRMT10A and TRMT10B Jane Jackman, Nathan Howell (OSBP alumni), Manasses Jora, Benjamin F Jepson, Patrick A Limbach 2019
EGL-38/Pax coordinates development in the Caenhorhabditis elegans egg-laying system through EGF pathway dependent and independent functions Allison M Webb Chasser (OSBP alumni), Ryan W Johnson, Helen M Chamberlin 2019
Elucidating the Molecular Mechanism of Ultrafast Pfr-State Photoisomerization in Bathy Bacteriophytochrome PaBphP Dongping Zhong, Dihao Wang (OSBP alumni), Yangzhong Qin, Sheng Zhang, Lijuan Wang, Xiaojing Yang 2019
Global analysis of protein synthesis in Flavobacterium johnsoniae reveals the use of Kozak-like sequences in diverse bacteria Zakkary McNutt, Kurt Fredrick, William D Baez, Bappaditya Roy, Elan A Shatoff, Shicheng Chen, Ralf Bundschuh 2019
Insights into Catalytic and tRNA Recognition Mechanism of the Dual-Specific tRNA Methyltransferase from Thermococcus kodakarensis Jane Jackman, Samantha Dodbele (OSBP alumni), Aiswarya Krishnamohan 2019
Intrinsic conformational dynamics of the HIV-1 genomic RNA 5'UTR Jonathan Kitzrow, Karin Musier-Forsyth, Benjamin S Brigham, Joshua-Paolo C Reyes, James B Munro 2019
Isolation of Proteins on Nascent Chromatin and Characterization by Quantitative Mass Spectrometry Miranda Gardner, Michael Freitas, Mark Parthun, Paula A Agudelo Garcia 2019
Mechanism of Cardiac Troponin C Calcium Sensitivity Modulation by Small Molecules Illuminated by Umbrella Sampling Simulations Steffen Lindert, Jacob D Bowman (OSBP alumni), William H Coldren 2019
Membrane-specific spin trap, 5-dodecylcarbamoyl-5-N-dodecylacetamide-1-pyroline-N-oxide (diC12PO): theoretical, bioorthogonal fluorescence imaging and EPR studies Claire Hoffman, Jeff Kuret, Colwyn A Headley, Juliana M Freisen, Yongbin Han, Joseph M Macklin, Jay L Zweier, Antal Rockenbauer, Frederick A Villamena 2019
Mineralocorticoid Receptor Signaling Contributes to Normal Muscle Repair After Acute Injury Zachary Howard, Federica Accornero, Jill Rafael-Fortney, J Spencer Hauck, Jeovanna Lowe, Neha Rastogi, Madison G Pico, Sarah A Swager, Jennifer M Pertosino, Celso E Gomez-Sanchez, Elise P Gomez-Sanchez 2019
Modeling Human Cancer-induced Cachexia Noah Weisleder, Melissa Siebert (OSBP alumni), Erin E Talbert, Maria C Cuitino, Katherine J Ladner, Priyani V Rajasekerea, Reena Shakya, Gustavo W Leone, Michael C Ostrowski, Brian Paleo, Peter Reiser, Amy Webb, Cynthia D Timmers, Daniel S Eiferman, David C Evans, Mary E Dillhoff, Carl R Schmidt, Dennis C Guttridge 2019
MtpB, a member of the MttB superfamily from the human intestinal acetogen Eubacterium limosum, catalyzes proline betaine demethylation Joseph Krzycki, Jonathan W Picking (OSBP alumni), Edward J Behrman, Liwen Zhang 2019
Multidomain Convergence of Argonaute during RISC Assembly Correlates with the Formation of Internal Water Clusters Hong Duc Chau Phan, Marcos Sotomayor, Kotaro Nakanishi, Daniel M Dayeh (OSBP alumni), Mi Seul Park, Raul Araya-Secchi, James A Brackbill, Audrey C Kehling, Ekram W Abd El-Wahab 2019
Oligomerization Affects the Ability of Human Cyclase-Associated Proteins 1 and 2 to Promote Actin Severing by Cofilins Dmitri Kudryashov, Vicki Wysocki, Vedud Purde (OSBP alumni), Florian Busch, Elena Kudryashov 2019
Phosphorylation of Arabidopsis eIF4E and eIFiso4E by SnRK1 inhibits translation David Bisaro, Aaron N Burns (OSBP alumni), Sizhun Li, Gireesha Mohannath 2019
Protein corona-resistant SERS tags for live cell detection of integrin receptors Brian Scarpitti, Zachary Schultz, Sian Sloan-Dennison, MaKenzie R Bevins, Victoria K Sauve 2019
Quantification of Tau Protein Lysine Methylation in Aging and Alzheimer's Disease Claire Hoffman, Jeff Kuret, Grace L Cooper (OSBP Alumni), Carol J Huseby, Jean-Christophe Cocuron, Ana P Alonso, Stefani N Thomas, Austin J Yang 2019