Publications

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Title Investigators Year
Identification of Small-Molecule Inhibitors of the Salmonella FraB Deglycase Using a Live-Cell Assay. Jamison Law, Venkat Gopalan, Anice Sabag-Daigle, Erin F Boulanger, Pankajavalli Thirugnanasambantham, Alex J Bogard, Edward J Behrman, Brian M M Ahmer 2023
Increased levels of eIF2A inhibit translation by sequestering 40S ribosomal subunits Daisy J Grove, Daniel J Levine, Michael G Kearse 2023
Integrative Multi-Omics Analysis of Oncogenic EZH2 Mutants: From Epigenetic Reprogramming to Molecular Signatures Julian Aldana, Miranda L Gardner, Michael A Freitas 2023
Mammary gland development and EDC-driven cancer susceptibility in mesenchymal ERα-knockout mice Clarissa Wormsbaecher, Brittney M Cumbia, Emma G Amurgis, Jillian M Poska, Madeline R Price, Xiaokui M Mo, Sue E Knoblaugh, Takeshi Kurita, Craig Joseph Burd 2023
Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex Islam E Elkholi, Jonathan Boulais, Marie-Pier Thibault, Hong-Duc Phan, Amélie Robert, Lien B Lai, Denis Faubert, Matthew J Smith, Venkat Gopalan, Jean-Franҫois Côté 2023
Minimal expression of dysferlin prevents development of dysferlinopathy in dysferlin exon 40a knockout mice Joe Yasa, Claudia E Reed, Adam M Bournazos, Frances J Evesson, Ignatius Pang, Mark E Graham, Jesse R Wark, Brunda Nijagal, Kim H Kwan, Thomas Kwiatkowski, Rachel Jung, Noah Weisleder, Sandra T Cooper, Frances A Lemckert 2023
Molecular mechanisms of Holliday junction branch migration catalyzed by an asymmetric RuvB hexamer Anthony Rish, Qingfei Zheng, Tianmin Fu, Zhangfei Shen, Zhenhang Chen, Nan Zhang 2023
MORF and MOZ acetyltransferases target unmethylated CpG islands through the winged helix domain Blanche Chen, Michael Poirier, Dustin C Becht , Brianna J Klein, Akinori Kanai, Suk Min Jang, Khan L Cox, Bing-Rui Zhou, Sabrina K Phanor, Yi Zhang, Christopher C Ebmeier, Catherine Lachance , Maxime Galloy, Amelie Fradet-Turcotte, Martha L Bulyk, Yawen Bai, Jacques Côté, Akihiko Yokoyama, Tatiana G Kutateladze 2023
NaV1.6 dysregulation within myocardial T-tubules by D96V calmodulin enhances proarrhythmic sodium and calcium mishandling Mikhail Tarasov, Heather L Struckman, Yusuf Olgar, Alec Miller, Mustafa Demirtas, Vladimir Bogdanov, Radmila Terentyeva, Andrew M Soltisz, Xiaolei Meng, Dennison Min, Galina Sakuta, Izabella Dunlap, Antonia D Duran, Mark P Foster, Jonathan P Davis, Dmitry Terentyev, Sándor Györke, Rengasayee Veeraraghavan, Przemysław B Radwański 2023
Oligomerization-mediated activation of a short prokaryotic Argonaute Zhangfei Shen, Xiao-Yuan Yang, Shiyu Xia, Wei Huang, Derek J Taylor, Kotaro Nakanishi, Tian-Min Fu 2023
Ribosomes lacking bS21 gain function to regulate protein synthesis in Flavobacterium johnsoniae. Zakkary McNutt, Kurt Fredrick, Roy B, Gemler BT, Shatoff EA, Moon KM, Foster LJ, Bundschuh R 2023
Role of Substrate Binding Interactions on DNA Repair by Photolyase Debanjana Chakraborty, Chao Yang, Lijuan Wang, Dongping Zhong 2023
Scribe: Next Generation Library Searching for DDA Experiments Brian Searle, Ariana Shannon, Damien Wilburn 2023
Structural basis of tRNAPro acceptor stem recognition by a bacterial trans-editing domain Xiao Ma, Marina Bakhtina, Irina Shulgina, William A Cantara, Alexandra B Kuzmishin Nagy, Yuki Goto, Hiroaki Suga, Mark P Foster, Karin Musier-Forsyth 2023
The inhibitor of κB kinase β (IKKβ) phosphorylates IκBα twice in a single binding event through a sequential mechanism Anthony A Stephenson, David J Taggart, Guozhou Xu, Jason D Fowler, Hao Wu, Zucai Suo 2023
The tRNA methyltransferase TrmB is critical for Acinetobacter baumannii stress responses and pulmonary infection Jenna C McGuffey, Clay D Jackson-Litteken, Gisela Di Venanzio, Aubree A Zimmer, Jessica M Lewis, Jesus S Distel, Kyusik Q Kim, Hani S Zaher, Juan Alfonzo, Nichollas E Scott, Mario F Feldman 2023
Translation reinitiation after uORFs does not fully protect mRNAs from nonsense-mediated decay Paul Russell, Arthur Burghes, Michael Kearse, Jacob A Slivka, Elaina P Boyle 2023
tRNA m1G9 modification depends on substrate-specific RNA conformational changes induced by the methyltransferase Trm10 Sarah E Strassler, Isobel E Bowles, Aiswarya Krishnamohan, Hyejeong Kim, Catherine B Edgington, Emily G Kuiper, Clio J Hancock, Lindsay R Comstock, Jane E Jackman, Graeme L Conn 2023
A tRNA-specific function for tRNA methyltransferase Trm10 is associated with a new tRNA quality control mechanism in Saccharomyces cerevisiae Isobel Bowles, Jane Jackman 2024
Accurate Quantification and Imaging of Cellular Uptake Using Single-Particle Surface-Enhanced Raman Scattering Brian Scarpitti, Zachary Schultz, Sanjun Fan, Madeleine Lomax-Vogt, Anthony Lutton, John W Olesik 2024
Analysis of programmed frameshifting during translation of prfB in Flavobacterium johnsoniae Fawwaz M Naeem, Bryan T Gemler, Zakkary A McNutt, Ralf Bundschuh, Kurt Fredrick 2024
Antagonistic Effects of Actin-Specific Toxins on Salmonella Typhimurium Invasion into Mammalian Cells David B Heisler, Elena Kudryashova, Regan Hitt, Blake Williams, Michelle Dziejman, John Gunn, Dmitri S Kudryashov 2024
Cell-type specific effects of mineralocorticoid receptor gene expression suggest intercellular communication regulating fibrosis in skeletal muscle disease Chetan K Gomatam, Pratham Ingale, Gabriel Rodriguez, Sarah Munger, Rachel Pomeranets, Swathy Krishna, Jeovanna Lowe, Zachary M Howard, Jill A Rafael-Fortney 2024
Characterization of ribosome stalling and no-go mRNA decay stimulated by the fragile X protein, FMRP MaKenzie R Scarpitti, Benjamin Pastore, Wen Tang, Michael G Kearse 2024
Copper binding alters the core structure of amyloid fibrils formed by Y145Stop human prion protein Vidhyalakshmi Sridharan, Tara George, Daniel W Conroy, Zach Shaffer, Witold K Surewicz, Christopher P Jaroniec 2024